OA of the knee-a prevalent condition that restricts daily activity

Develop a schedule and stick to it.
Before long, PENNSAID can be a part of your everyday routine.

Pick 4 times in your day that are easy to remember.

Exercise can help you have less pain, be more flexible, and enjoy a more positive attitude. Talk to your doctor about the forms of exercise that are best for you.

To help you get started, you can use a Movement Tracker.
The Movement Tracker is a FREE online tool that helps you create personalized goals that will keep you and your joints moving year-round.

Create your personalized goals with the FREE
Movement Tracker at www.arthritis.org.

Weight loss can reduce the stress put on your knees and increase your ability to get around. Even small amounts of weight loss can make a difference.

For each pound of weight you lose,
you take 4 pounds of stress off your knees.

Lack of sleep has been linked to more pain and illness. If you have trouble sleeping, talk to your doctor about ways of making your sleep better.

Listening to soothing music may help
relax muscles and help you get to sleep.

Altman RD. Practical considerations for the pharmacologic management of osteoarthritis. Am J Manag Care. 2009;15:S236-S243. Arthritis Foundation. All about Osteoarthritis. http://www.arthritistoday.org. Accessed January 6, 2011. Arthritis Foundation. NSAIDs. Arthritis Today Drug Guide. http://www.arthritistoday.org/treatments/drug‑guide/types‑of‑drugs/drug‑guide‑nsaids.php. Accessed January 6, 2011. Arthritis Foundation. NSAIDs. Who gets osteoarthritis. http://www.arthritis.org/who‑gets‑osteoarthritis.php. Accessed January 6, 2011. Arthrotec (diclofenac sodium/misoprostol) Tablets USP [prescribing information]. New York, NY: G.D. Searle LLC, Division of Pfizer. Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol. 1988;15:1833-1840. Diclofenac sodium delayed release tablets USP [prescribing information]. Corona, CA: Watson Laboratories, Inc. Evans JMM, McMahon AD, McGilchrist MM, et al. Topical non-steroidal anti-inflammatory drugs and admission to hospital for upper gastrointestinal bleeding and perforation: a record linkage case-control study. Br Med J. 1995;311:22-26. Heyneman CW, Lawless-Liday C, Wall GC. Oral versus topical NSAIDs in rheumatic diseases: a comparison. Drugs. 2000;60:555-574. Notman R, Noro M, O’Malley B, Anwar J. Molecular basis for dimethylsulfoxide (DMSO) action on lipid membranes. J Am Chem Soc. 2006;128:13982-13983. PENNSAID [package insert]. Mississauga, Ontario:Nuvo Research, Inc.; 2010.

INDICATION
PENNSAID® is a nonsteroidal anti-inflammatory drug (NSAID) used for treating the signs and symptoms of osteoarthritis of the knee(s).

IMPORTANT RISK INFORMATION

WARNING: CARDIOVASCULAR (CV) AND GASTROINTESTINAL (GI) RISK
    Cardiovascular Risk
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of serious blood clots in the heart, or cause a heart attack or stroke. These risks can cause death. The risk may increase the longer NSAIDs are used. Patients who have heart disease or are at risk for heart disease may be at greater risk
  • Do not use PENNSAID in patients who are in the hospital for heart bypass surgery grafts
    Gastrointestinal Risk
  • NSAIDs cause an increased risk of serious stomach problems or problems in the intestines. Patients could bleed or develop a hole in their stomach or intestines. All of these problems can cause death. These problems can happen at any time with no warning when using NSAIDs. Older patients are at greater risk for these problems

COVIDIEN, COVIDIEN with logo and Covidien logo are U.S. and internationally registered trademarks of Covidien AG.
PENNSAID is a registered trademark of Nuvo Research Inc. Other brands are trademarks of their respective owners. © 2011 Covidien